Thursday, June 20, 2013

Zimbabwe's president goes back to court on polls

HARARE, Zimbabwe (AP) ? Zimbabwe's highest court said Wednesday it has received an application from longtime President Robert Mugabe's party to delay crucial elections by at least two weeks following pressure from regional leaders.

Mugabe has insisted he is merely abiding by a previous court order in holding general elections on July 31. Prime Minister Morgan Tsvangirai, a longtime Mugabe foe and opposition leader, wants the vote to be held in September.

Zimbabwe's last elections in 2008 were plagued by violence and ultimately forced Mugabe to join a power-sharing government with the opposition.

Officials at the Constitutional Court say the papers submitted by Mugabe's party ask the court to review the earlier ruling that called for a vote before the end of July.

The move comes days after southern African regional leaders met in Mozambique and pushed for an extension until Aug. 14 so that key electoral reforms and poll preparations can take place.

Justice Minister Patrick Chinamasa said in the papers filed at the constitutional court that he was directed by a summit of the regional presidents in Mozambique to file an urgent application to postpone the elections and asked for an extension to Aug. 14, court officials said.

Tomaz Salomao, secretary-general of the 15-nation regional, political and economic bloc known as the Southern African Development Community, or SADC, said Tuesday the presidents had urged Mugabe and all political groups to heed their concerns over early elections. He said the SADC grouping pledged to recognize any new decision by Zimbabwe's highest court.

"If the court does not accept the appeal our task is to deploy our observers to ensure there is at least a conducive environment for elections," he said.

Tsvangirai insists new elections can be called as late as October under the nation's new constitution to allow time for democratic reforms spelled out in both the power-sharing coalition agreement and the constitution to be put into place to pave the way for a free and fair vote.

His party says a two-week extension is still inadequate to complete reforms to sweeping media and security laws, and changes in the police, military and security services traditionally loyal to Mugabe to ensure their impartiality.

Mugabe declared the July poll date on June 13, saying he was obeying the ruling of the Constitutional Court that linked the need for elections to a month after the automatic dissolution of the Harare parliament at the end of its current five-year term on June 28.

His announcement on the voting date meant the drafting of amendments to long-standing elections laws were frozen on legal and procedural grounds.

No date was immediately set for the appeal before the bench of nine judges at the Constitutional Court.

Source: http://news.yahoo.com/zimbabwes-president-goes-back-court-polls-112214753.html

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3-D Printer Brings Dexterity To Children With No Fingers

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3-D Printer Brings Dexterity To Children With No Fingers
An enterprising carpenter and a creative puppeteer teamed up on a do-it-yourself project to build a mechanical hand for a little boy. They created an inexpensive prosthetic and published their designs on the Internet. So far, over 100 children have been outfitted.

Source: NPR
Posted on: Tuesday, Jun 18, 2013, 7:59am
Views: 7

Source: http://www.labspaces.net/128657/__D_Printer_Brings_Dexterity_To_Children_With_No_Fingers

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Tuesday, June 18, 2013

GEAK unveils Eye and Mars smartphones with 13MP cameras, budget prices

GEAK Eye and Mars smartphones

GEAK may be focusing its attention on wearable tech like the Ring and Watch, but it still has a pair of new offerings for those who like old-fashioned smartphones: meet the 5-inch Eye and 5.8-inch Mars. Both are tailored to photo junkies with 13MP, backside-illuminated rear cameras as well as strong front cameras that shoot at 8MP (Eye) and 2MP (Mars). Differences between the handsets revolve mostly around performance and screen size. The Eye keeps things modest with a 720p IPS display, a quad-core MediaTek MT6589, HSPA+ data, 1GB of RAM and 16GB of storage. Spring for the extra-large Mars and you'll upgrade to a 1080p IPS LCD, a Snapdragon 600 and 2GB of RAM. Either way, you won't be paying a lot for the imaging prowess -- when pre-orders start on June 25th, GEAK will ask ¥1,999 ($326) off-contract for the Eye and ¥2,999 ($490) for the Mars. Just don't expect either to leave China when there's no word of international plans.

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Via: Engadget Chinese (translated)

Source: GEAK (1), (2)

Source: http://www.engadget.com/2013/06/17/geak-unveils-eye-and-mars/?utm_medium=feed&utm_source=Feed_Classic&utm_campaign=Engadget

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Monday, June 17, 2013

Sunday, June 16, 2013

Turkish PM supporters turn out in force at rally

SINCAN, Turkey (AP) ? Tens of thousands of supporters of Prime Minister Recep Tayyip Erdogan are rallying in a suburb of Turkey's capital.

It amounted to a powerful show of support as his government faces down protesters holed up in an Istanbul park for the last two weeks.

The flag-waving Erdogan supporters converged Saturday in Sincan ? a suburb of the capital Ankara that is a stronghold of his Justice and Development Party.

Organizers hoisted a giant poster of Erdogan above a platform where he was expected to speak later.

Earlier Saturday, protesters at Istanbul's Gezi Park vowed to press on with their two-week sit-in there, defying government appeals and a warning from Erdogan for an end to the standoff. The sit-in has become one of the most public challenges to his decade-long tenure.

Source: http://news.yahoo.com/turkish-pm-supporters-turn-force-rally-143247572.html

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U.S. considering no-fly zone in Syria

By Parisa Hafezi and Erika Solomon

ANKARA/BEIRUT (Reuters) - The United States is considering a no-fly zone in Syria, potentially its first direct intervention into the two-year-old civil war, Western diplomats said on Friday, after the White House said Syria had crossed a "red line" by using nerve gas.

After months of deliberation, President Barack Obama's administration said on Thursday it would now arm rebels, having obtained proof the Syrian government used chemical weapons against fighters trying to overthrow President Bashar al-Assad.

Two senior Western diplomats said Washington is looking into a no-fly zone close to Syria's southern border with Jordan.

"Washington is considering a no-fly zone to help Assad's opponents," one diplomat said. He said it would be limited "time-wise and area-wise, possibly near the Jordanian border", giving no further details.

Imposing a no-fly zone would require the United States to destroy Syria's sophisticated Russian-built air defenses, thrusting it into the war with the sort of action NATO used to help topple Muammar Gaddafi in Libya two years ago. Washington says it has not ruled it out, but a decision is not "imminent".

"We have not made any decision to pursue a military operation such as a no-fly zone. And we have a range of contingency plans that we've drawn up," U.S. Deputy National Security Adviser Ben Rhodes said on Thursday.

"A no-fly zone ? would carry with it great and open-ended costs for the United States and the international community. It's far more complex to undertake the type of effort, for instance, in Syria than it was in Libya."

Any such move would also come up against a potential veto from Assad's ally Russia in the U.N. Security Council. The Kremlin dismissed U.S. evidence of Assad's use of nerve gas.

"I will say frankly that what was presented to us by the Americans does not look convincing," President Vladimir Putin's senior foreign policy advisor Yuri Ushakov said. "It would be hard even to call them facts."

France said a no-fly zone would be impossible without U.N. Security Council authorization, which made it unlikely for now.

Nevertheless, Washington has quietly taken steps that would make it easier, moving Patriot surface-to-air missiles, war planes and more than 4,000 troops into Jordan in the past week, officially as part of an annual exercise but making clear that the assets could stay on when the war games are over.

Syria's civil war grew out of protests that swept across the Arab world in 2011, becoming by far the deadliest of those uprisings and the most difficult to resolve, with powers across the Middle East squaring off on sectarian lines.

OBAMA'S CALCULUS

Western countries have spent the past two years demanding Assad leave power but declining to use force as they did in Libya, because of the far greater risk of fighting a much stronger country that straddles sectarian divides at the heart of the Middle East and is backed by Iran and Russia.

Just months ago, Western countries believed Assad's days were numbered. But momentum on the battlefield has turned in his favor, making the prospect of his swift removal and an end to the bloodshed appear remote without outside intervention.

Thousands of seasoned fighters from Lebanon's pro-Iranian Hezbollah militia joined the war on Assad's behalf in recent weeks and last week helped the Syrian government recapture Qusair, a strategic town. Assad's government says its troops are now preparing for a massive assault on Aleppo, Syria's biggest city, mainly in rebel hands since last year.

Activists reported an intensified assault on parts of Aleppo and its countryside near the Turkish border overnight, sparking some of the most violent clashes in months.

The use of chemical weapons provides a straightforward reason for Washington to intervene. Deputy National Security Adviser Rhodes said Washington now believed 100-150 people had been killed by government poison gas attacks on rebels.

"The president ... has made it clear that the use of chemical weapons or transfer of chemical weapons to terrorist groups is a red line," he said. "He has said that the use of chemical weapons would change his calculus, and it has."

Syria, which says rebels used chemical weapons not the government, said the U.S. statement was full of lies.

"The White House ... relied on fabricated information in order to hold the Syrian government responsible for using these weapons, despite a series of statements that confirmed that terrorist groups in Syria have chemical weapons," the foreign ministry said in a statement.

An implicit threat to join the conflict puts Washington on a diplomatic collision course with Moscow, which has used its U.N. Security Council veto three times to block resolutions that might be used to threaten force against Assad.

U.S. officials say Obama will try to persuade Putin to abandon support for Assad when the two leaders meet at a G8 summit in Northern Ireland next week.

Washington and Moscow have jointly called for a peace conference in Geneva, the first attempt in a year by the Cold War foes to find a diplomatic solution to the war, but the prospects for the talks now seem in doubt.

The United Nations now estimates at least 93,000 people have been killed in Syria and millions driven from their homes.

The arrival of thousands of Iran-backed Shi'ite Hezbollah fighters to help Assad combat a revolt led by Syria's Sunni majority has shifted momentum and raised the prospect of sectarian violence spreading across the Middle East.

Western powers have been reluctant in the past to arm the rebels, worried about the rising strength of Sunni Islamist insurgents among them who have pledged loyalty to al Qaeda. European countries like France say the best way to counter such Islamists is to provide more support for mainstream rebels.

The White House said Washington would now provide "direct military support" to the opposition. A U.S. official, speaking on condition of anonymity, confirmed it would now include arms as opposed to "non-lethal" aid sent in the past.

That puts once-reluctant Washington a step in front of its allies Paris and London, which have forced the European Union to drop a ban on arming the rebels this month but still say they have not yet taken a decision to send arms.

Syrian rebels already receive light arms from Saudi Arabia and Qatar. They have asked for heavier weapons including anti-tank and anti-aircraft missiles.

U.S. and European officials are meeting the commander of the rebels' Supreme Military Council, Salim Idriss, on Friday in Turkey.

Qassem Saadedine, a Supreme Military Council commander, called Obama's decision to send weapons "very brave".

"Our hope is that the weapons will start arriving in the coming weeks, but we are still in talks about when and how to supply weapons. My hope is we will start seeing a change in the next two weeks."

Islamist rebel fighters on the ground in Syria were more skeptical. "All of us inside Syria know the truth is America hates Sunni Muslims," said Abu Bilal, a Sunni insurgent in Homs.

"We consider America an enemy and see it as quite unlikely that it will actually give the mujahideen weapons. Instead it will be preparing its own agenda, so that it can hit the rebels just like it will hit the regime," he told Reuters via Skype.

An Islamist field commander in Hama said he would take the weapons if he could get them: "Everyone here right now is working on the principle that their enemy's enemy is their friend. America is against Bashar right now, at least publicly."

"As for us, we will look at the issue this way: we do not object to groups that take weapons from America. We will object to those who try to spread its secular ideas in Syria."

FIGHT FOR ALEPPO

Assad forces tried overnight to storm the rebel-held eastern districts of Aleppo, Syria's biggest city and commercial hub, according to the Syrian Observatory for Human Rights, a Britain-based, pro-opposition monitoring group.

The move sparked some of the fiercest battles in months. Activists also reported artillery and air strikes in the rebel-held countryside in the north of the province.

Syrian state media have been touting plans for "Northern Storm," a looming campaign to recapture the rebel-held north.

Aleppo would be a far more difficult target than Qusair. Assad's forces only hold a few routes and pockets of territory in the province, mostly in isolated Shi'ite villages.

Assad's main advantage so far has been the ability to use air power to resupply troops and bomb rebel areas, along with its use of long-range missiles. But Western support for rebels or a no-fly zone would change the current balance of power.

(Additional reporting by Erika Solomon in Beirut, John Irish in Paris; Khaled Yacoub Oweis in Amman, Matt Spetalnick, Roberta Rampton, Mark Felsenthal, Jeff Mason and Susan Heavey in Washington; Writing by Peter Graff and Erika Solomon; editing by Janet McBride)

Source: http://news.yahoo.com/u-says-assad-forces-used-chemical-weapons-against-000953375.html

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Saturday, June 15, 2013

China's Shenzhou 10 ship docks with space lab

BEIJING (AP) ? China's latest manned space capsule docked with an orbiting space station Thursday, and the three astronauts climbed aboard what will be their home for the next week, state media reported.

Automated controls guided the Shenzhou-10's docking with the space lab, the Xinhua News Agency said. After entering the space lab, the crew exchanged their space gear for blue jumpsuits, Xinhua said.

During their 12-day stay at the lab, the astronauts will perform a manual docking exercise and conduct scientific experiments. They will also deliver a series of science lectures ? part of an outreach to increase the space program's popularity among younger Chinese.

The lab, the Tiangong-1, is an experimental space station. In operation for less than two years, it will be taken out of use later this year and replaced by a larger, more durable module by 2020.

The latest Shenzhou flight the fifth manned mission in a decade in a program that has been marked by methodical advances to catch up with the other two manned space powers ? Russia and the U.S.

Source: http://news.yahoo.com/chinas-shenzhou-10-ship-docks-space-lab-084759734.html

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Friday, June 14, 2013

Skyjacker of the Day

130613_skyjackersCini

Illustrations by Ellie Skrzat

In the late 1960s and early 1970s, the United States suffered through a skyjacking epidemic that has now been largely forgotten. In his new book, The Skies Belong to Us: Love and Terror in the Golden Age of Hijacking, Brendan I. Koerner tells the story of the chaotic age when jets were routinely commandeered by the desperate and disillusioned. In the run-up to his book?s publication on June 18, Koerner has been writing a daily series of skyjacker profiles. Slate is running the final dozen of these ?Skyjacker of the Day? entries.

Flight Info: Air Canada Flight 812 from Vancouver to Toronto, with a scheduled stop in Calgary

The Story: At a congressional hearing in 1969, a Federal Aviation Administration psychologist named John Dailey testified that skyjackers were primarily motivated by a need for public recognition. ?He is like the Indian scalp hunter,? said Dailey. ?If the other Indians didn?t know when he scalped someone, he wouldn?t do it.? That statement may have been a gross overgeneralization, but it certainly applied to Paul Joseph Cini, a man who botched his quest for fame by tying a knot too tightly.

In September 1970, while downing shots of vodka in his Victoria, British Columbia, apartment, Cini had watched a television news segment about a failed hijacking for ransom. In the midst of the story, his alcohol-fuzzed mind somehow managed to produce a eureka moment: The best way for a hijacker to escape justice was not to fly abroad, but rather to jump from the plane.

Cini initially had no designs on attempting this himself, as he was deathly afraid of heights?during his brief stint in the Canadian army, in fact, he had been too petrified to scale a telephone pole during a training exercise. But the more he contemplated the risky caper, the more he became convinced that it represented his one shot at improving his lackluster life, which was marred by alcoholism and dim job prospects. ?I wanted recognition,? he would later explain. ?I wanted to stand up and say, ?Hey, I?m Paul Cini, and I?m here and I exist and I want to be noticed.? ?

Cini boarded Flight 812 in Calgary with a bag containing everything he thought he would need to pull off the hijacking and then survive in the wilderness after jumping from the plane: a sawed-off shotgun, dynamite, a sheepskin rope, a collapsible shovel, a pup tent, candy bars, hiking boots, and a dark-blue parachute wrapped in a paper bag. After downing several Screwdrivers, he brandished the weapons and announced that he was a member of the Irish Republican Army who would blow up the DC-8 unless he was given $1.5 million and passage to Ireland. The plane landed in Great Falls, Mont., where Cini received all the cash that Air Canada could muster on short notice?a mere $50,000. Unlike fellow hijacker Arthur Gates Barkley, who had freaked out when TWA shorted him by $99,899,250, Cini didn?t mind the lesser ransom.

The DC-8 was en route back to Calgary to refuel when Cini told the crew to open one of the emergency exits so he could jump to freedom. But try as he might, Cini couldn?t undo the twine that he had used to wrap his parachute?the knot was too tight, especially for a man whose fine motor skills were impaired by copious amounts of liquor.

The frustrated Cini asked one of the pilots to lend him a sharp instrument to cut free his parachute. When the pilot offered him the DC-8?s fire ax, Cini absentmindedly laid down his shotgun to accept it. Seeing that the hijacker was now unarmed, the pilot kicked away the shotgun and grabbed Cini by the throat. Another crew member took the ax and smashed it into Cini?s head, fracturing his skull. Paul Joseph Cini would be remembered not as the world?s first ?parajacker? but as a fool.

The Upshot: The fame that Cini so desperately craved would instead go the fabled D.B. Cooper, who jumped out of a Northwest Orient Airlines jet 11 days later and was never seen again. Cini was sentenced to life in prison in April 1972, though he was paroled after serving just 10 years.

Source: http://www.slate.com/articles/life/history/features/2013/skyjacker_of_the_day/paul_joseph_cini_hijacked_a_plane_because_he_had_an_idea_parachuting.html

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GOP congressman: Rate of pregnancies from rape is 'very low' (Washington Post)

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Friday, June 7, 2013

Derby winner Orb 3-1 favorite for Belmont

(AP) ? Kentucky Derby winner Orb has been made the morning-line favorite in a field of 14 horses entered for the Belmont Stakes.

Preakness winner Oxbow is the third choice in the largest Belmont field since 1996. Orb is the 3-1 favorite and drew the No. 5 post for trainer Shug McGaughey. Oxbow is 5-1 after drawing the No. 7 post for trainer D. Wayne Lukas.

Todd Pletcher has a record five 3-year-olds in the 1?-mile race. Among them is Unlimited Budget, who will attempt to become the fourth filly to win the final leg of the Triple Crown. His other entries are Overanalyze, Palace Malice, Revolutionary and Midnight Taboo. Revolutionary is the second choice at 9-2.

Also entered Wednesday are Frac Daddy, Freedom Child, Giant Finish, Golden Soul, Incognito, Vyjack and Will Take Charge.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/347875155d53465d95cec892aeb06419/Article_2013-06-05-RAC-Belmont-Stakes/id-c6240921cdb7450d9f4a74f441531155

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Sunday, February 24, 2013

Lyoto Machida pulls out split-decision win over Dan Henderson at UFC 157

ANAHEIM, Calif. -- Lyoto Machida took a split decision over Dan Henderson in the co-main event at UFC 157 on Saturday. The judges saw it 29-28, 28-29, 29-28 for Machida.

Machida was elusive as usual in the first round, but Henderson was able to sneak in and land a few kicks and punches. At the end of the round, Machida took Henderson down with a leg trip and landed strikes.

The second round showed Machida still being elusive and keeping his distance from Henderson. Machida tried for a front kick several times, but couldn't land it. Meanwhile, Henderson couldn't land much.

[Also: Ronda Rousey survives UFC debut, wins via first-round arm bar]

Henderson is known for his big, overhand punches. Most of the time, when he throws it, it can mean the end of a fight. However, he had trouble getting close enough to Machida for the overhand to work.

In the third round, Machida moved in for a takedown but ended up with Henderson on top. Henderson used elbows from the top, but Machida was able to get out with less than two minutes left in the fight.

Before the fight, UFC president Dana White said that the winner of this bout will get the next title shot. UFC light heavyweight champion Jon Jones will put the title up against Chael Sonnen in April, but the next fight will likely go to Machida.

[Also: Josh Koscheck suffers upset loss]

Machida was once the UFC light heavyweight champion, but lost the title to Rua in 2010. Since then, he has wins over Randy Couture and Ryan Bader, but losses to current champion Jon Jones and Quinton Jackson. It will be his third chance at the light heavyweight title. He won it with a knockout of Rashad Evans in 2009, but lost to Jones in 2011.

Henderson had a long layoff between fights. His last bout was one of the best in MMA history. In November of 2011, Henderson defeated Mauricio Rua in a five-round decision. Since then, Henderson had a fight lined up with Jones in September, but had to pull out at the last minute because of a knee injury. His record falls to 29-9. He's 42 years old, and against Machida, looked slow and old for the first time in his career.

Other popular content on Yahoo! Sports:
? Watch: Floyd Mayweather's college football betting secret
? Michael Jordan gets minor league offer
? Alex Smith on the trading block in Indy
? Wake Forest knocks off No. 2 Miami

Source: http://sports.yahoo.com/blogs/mma-cagewriter/lyoto-machida-pulls-split-decision-win-over-dan-045605104--mma.html

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Saturday, February 23, 2013

Israeli forces, Palestinians clash throughout West Bank

RAMALLAH, West Bank (Reuters) - Israeli forces clashed with Palestinian protesters throughout the occupied West Bank on Friday, capping a week of violence amid a hunger strike by four Palestinians in Israeli jails.

Tension and anticipation is rising in the West Bank a month before U.S. President Barack Obama is due to visit Jerusalem and Ramallah, though he has announced no concrete plans to revive Israeli-Palestinian peace talks stalled for three years.

From the precincts of Jerusalem's al-Aqsa mosque, both one of Islam's holiest sites and revered by Jews as the site of their Biblical temple, youths threw stones at Israeli police after Friday prayers.

Dozens of Israeli officers briefly entered the politically sensitive compound. Witnesses said officers fired tear gas and threw percussion grenades at the demonstrators as bystanders and elderly worshippers ran for cover.

A police spokesman said no tear gas was fired, but that protesters were throwing firecrackers.

The old city of Hebron, a bitterly contested city in the southern West Bank sown heavily with Israeli settlers, echoed with percussion grenades hurled by Israeli forces at some 1,500 Palestinian protesters.

At a military checkpoint near the northern city of Nablus and outside a military prison in the central West Bank, Israeli forces worked to clear away makeshift roadblocks and fired rubber bullets towards stone-throwing Palestinians.

There were dozens of light injuries from gas inhalation and rubber and aluminum bullets, witnesses said.

Palestinians seek statehood in territories Israel captured in a 1967 war. Peace talks broke down in 2010 over Palestinian objections to Israel expanding settlements on occupied land. Israel has called for resuming the talks without preconditions.

HUNGER STRIKERS IN LIMBO

The status of four hunger-striking Palestinian detainees was in limbo as Israeli civilian courts failed to rule definitively in hearings held for two of them this week, referring their multi-decade sentences back to military courts.

Israel convicted the men of taking part in militant attacks and freed them along with hundreds of other prisoners in a 2011 swap for Gilad Shalit, an Israeli soldier held in Hamas-ruled Gaza for five years, only to re-arrest them soon afterward.

Lawyers and officials representing the men, who were accused by Israel of violating the terms of their release, say their cases are locked in a legal maze and Palestinian officials hope Egyptian mediation could convince Israel to free them.

"Our prisoners ...(on) hunger strike are engaging in a true battle, a battle of glory against the tyrant," said Ismail Haniyeh, Gaza's Hamas prime minister. "No one of us will forget the prisoners. No one would enjoy being with his children at home as long as those heroes continued to suffer in jails."

The hunger strikers have told representatives of an independent Israeli medical group, Physicians for Human Rights, that they are taking water but refusing medicines and nutrients.

There is little exact information on the health of the strikers, whose on-off hunger strikes have ranged from around 80 to over 200 days, as they have repeatedly refused treatment and been denied regular access to independent doctors.

Israel holds around 4,700 Palestinians in its prison on charges ranging from throwing stones to killing Israelis.

Palestinians widely regard them as heroes of their national struggle against Israel and want them all freed.

(Reporting By Noah Browning; Editing by Mark Heinrich)

Source: http://news.yahoo.com/israeli-forces-palestinians-clash-throughout-west-bank-135638177.html

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Friday, February 22, 2013

Chill turns monarchs north

Cold weather flips butterflies? migratory path

By Meghan Rosen

Web edition: February 21, 2013

Enlarge

BUTTERFLY EFFECT

Monarchs stop for nectar during their migration south. The butterflies don?t live long enough to complete a full round trip, making it a mystery as to how they know when to head north.

Credit: Courtesy of Monarch Watch

Scientists have pinned down the answer to a long-standing butterfly mystery: what flips monarchs? migratory compasses. A little cold weather may be all that?s needed. Just 24 days in a chilly lab incubator is enough to switch a butterfly?s flight orientation from south to north, researchers report online February 21 in Current Biology.

?It?s pretty doggone cool,? says insect ecologist Orley ?Chip? Taylor of the University of Kansas, who was not involved in the new research. But the finding is also disturbing, he says. ?It suggests that as temperatures warm, monarchs may be in trouble.?

Each fall, in a massive monarch migration, millions of butterflies set off on a journey from their northern range to central Mexico to escape freezing winters. Nestled among Mexico?s Michoac?n mountains, the butterflies cling to tree branches, huddled together in roosts to fend off the cold. ?They sort of snuggle each other,? says study author Steven Reppert of the University of Massachusetts Medical School in Worcester. The snuggling creates a cozy microenvironment that buffers high and low temperatures.

Enlarge

HOMEWARD BOUND

Cued after a cold winter, a tattered and torn monarch journeys back home in the spring.

Credit: P.A. Guerra and S.M. Reppert/Current Biology 2013

Migrating to and overwintering in Mexico is tough work: The long journey strips the black-and-orange monarchs of their vibrant colors and tatters their wings. These old travelers are ?battle worn,? Reppert says. ?But they?re still troopers.? In the spring, when the monarchs begin their voyage back, he says, ?even though their wings are beat up, they fly like crazy ? moving ahead like nobody?s business.? The travel-weary butterflies are strong enough to start the journey north, find food and reproduce. Then their descendents finish the trip home.

Until now, researchers didn?t know what triggered the trek north. They suspected environmental factors such as temperature or changing day length could cue the monarchs. To find out, Reppert?s team studied southward-migrating monarchs captured in the eastern United States. The scientists housed one group of migrants in an incubator for 24 days and turned down the temperature to 4? Celsius during dark ?night? periods and 11? C during light ?day? periods ? the average temperatures in the wintertime butterfly roosts. The team exposed a second group of butterflies to the same temperatures while also simulating the subtle increase in daylight that monarchs see over the winter while in Mexico.

Then the researchers took the two groups outside and tethered them one by one inside a flight simulator ? a white plastic barrel that gauges flight bearings. In both experimental groups, the lab-wintered butterflies flew north. In fact, Reppert says, ?the data were identical.?

Also, southern-migrating monarchs that had been captured in Texas and kept in the lab under fall conditions ? with no pulse of nightly cold temperature ? continued to head south when hooked up to the flight simulator.

?It?s astounding,? says ecologist Karen Oberhauser of the University of Minnesota, who supplied captured butterflies to Reppert?s team. She?s convinced that just 24 days of cold temperature is enough to switch butterflies? flight direction from south to north. But she?s also curious about the effects of day length alone.

Reppert says the direction trigger might be modified by changes in day length, but ?clearly coldness is the main factor.? Next, his team hopes to figure out exactly how the monarchs sense temperature.

Source: http://www.sciencenews.org/view/generic/id/348485/title/Chill_turns_monarchs_north

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Tuesday, February 12, 2013

Introduction to Real Analysis: An Educational Approach


 Introduction to Real Analysis: An Educational Approach others
Introduction to Real Analysis: An Educational Approach
English | PDF | 262 Pages | 10.1 Mb

An accessible introduction to real analysis and its connection to elementary calculus
Bridging the gap between the development and history of real analysis, Introduction to Real Analysis: An Educational Approach presents a comprehensive introduction to real analysis while also offering a survey of the field. With its balance of historical background, key calculus methods, and hands-on applications, this book provides readers with a solid foundation and fundamental understanding of real analysis.

The book begins with an outline of basic calculus, including a close examination of problems illustrating links and potential difficulties. Next, a fluid introduction to real analysis is presented, guiding readers through the basic topology of real numbers, limits, integration, and a series of functions in natural progression. The book moves on to analysis with more rigorous investigations, and the topology of the line is presented along with a discussion of limits and continuity that includes unusual examples in order to direct readers? thinking beyond intuitive reasoning and on to more complex understanding. The dichotomy of pointwise and uniform convergence is then addressed and is followed by differentiation and integration. Riemann-Stieltjes integrals and the Lebesgue measure are also introduced to broaden the presented perspective. The book concludes with a collection of advanced topics that are connected to elementary calculus, such as modeling with logistic functions, numerical quadrature, Fourier series, and special functions.

Detailed appendices outline key definitions and theorems in elementary calculus and also present additional proofs, projects, and sets in real analysis. Each chapter references historical sources on real analysis while also providing proof-oriented exercises and examples that facilitate the development of computational skills. In addition, an extensive bibliography provides additional resources on the topic.

Introduction to Real Analysis: An Educational Approach is an ideal book for upper- undergraduate and graduate-level real analysis courses in the areas of mathematics and education. It is also a valuable reference for educators in the field of applied mathematics.


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Source: http://wowebook.net/2013/02/introduction-to-real-analysis-an-educational-approach.html

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Tuesday, February 5, 2013

Why do I feel like I have psychic abilities?

Why do I feel like I have psychic abilities?
I feel like I have psychic abilities but I just dont know how to use them. I feel like I need to learn them, this is very hard to explain. Who should I go to get help for this and how can I improve them? No skeptics please. Thanks!

Suggestion by BJ Jackson
I actually practice psychic abilities. Really everyone has them it just takes the practice and patients to control them and use them to your advantage. If you really want a deeper understanding you should check out this website: psipog.net

Suggestion by Shenaynay
I suppose you feel that you have psychic abilities because you are fooling yourself like all the other people that like to imagine that have magical powers.

Now instead of saying ?no skeptics? just go ahead and do something to prove you have the abilities you claim and then no one need be skeptical any more.

Suggestion by advisor
Just keep an open mind unlike the skeptics who cannot stay away even when asked politely.

Give your answer to this question below!

Why is it that people believe women are more open to psychic abilities?
I have heard that women are just naturally more open to their psychic abilities and esp type of things. What makes that so?

Suggestion by ZelosWilder
In general, women have richer fantasy lives. So they?re more willing to believe that they are psychic.

Suggestion by Anonymous
Women are more observant of body language, tone, and movement.

It isn?t that women are ?More Open? to anything, it is just that women are WAY MORE innately aware of things that men are not DESIGNED to notice.

It goes along with the idea of ?Cold Reading?. You ask questions, watch reactions, and then tailor your response to those reactions.

Women exist on more then 1 level? We see the ?Big Stuff? like cars and trees and people? But we have a 2nd level that is even more observant then what we consciously see.

Men are designed to be able to find the deer in the brush?
Women are designed to read the look on their child?s face and understand what they are feeling and, to a lesser extent, what they are thinking.

We are not even really ?Aware? that all this extra analysis is going on? It just happens as instinctually as birds know to fly south?

?Normal? women just go with it and accept it as the natural, biological ability that it is?

People with low self esteem or that crave attention or have no problem screwing money out of gullible people? They are another animal all together?

THEY take ?I knew my best friend was going to call and that my father was going to tell me that something bad had happened? from normal and put such greater meanings on it that they CONVINCE THEMSELVES that they have ?powers?.

Most of these people TRULY THINK they have powers? You hear it all the time even here on Y!A?

?I have the gift and I never ask for money, you don?t know what you are talking about.? Etc.

People that NEED MORE in their lives may turn to religion and say they see Jesus in the wood grain on their bathroom door?

As seen here:
Penn & Teller: Signs from Heaven Part 1

http://www.youtube.com/watch?v=jHH5qeA5S54&feature=related

Penn & Teller: Signs from Heaven Part 2

http://www.youtube.com/watch?v=6Qq13BKPO7g&feature=related

Penn & Teller: Signs from Heaven Part 3

http://www.youtube.com/watch?v=wsS2kXd9r40&feature=related

Then others delude themselves that they have magic powers that make them ?Special?.

It all boils down to the NEED to feel special? And be that ?Special? in the eyes of their god or ?Special? as in ?I can see the future and talk to dead people? it is all the same?

A desperate cry for attention.

Suggestion by Bisexual Bullet
I think that psychic abilities are felt through your emotional level of feeling.

Add your own answer in the comments!

What is the difference between hallucinating and psychic ability?
And what I mean by the psychic ability, I mean like seeing the dead or spirits and other stuff like that. You know what I mean? How can you determine if someone is just hallucinating or actually has psychic abilities?

Suggestion by Stacie C
If someone has abilities, they would most likely be very hush hush about it. A good way to find out is to see if the person has done anything that would give them hallucinations. Drugs? Mental Illness? Lack of sleep? History of mental illness in the family?

Suggestion by Tukmyhamster
In my opinion no one has psychic abilities, since such an ability has never been shown to be real when tested under controlled conditions on the other hand I don?t think the majority of people that claim to be psychic are hallucinating either. To me it seems more like wishful thinking, imagining things, and bending the data.

People make a few general guesses, remember the things they get right and mentally discard the things they get wrong so in the end they are left with the idea that they are getting a load of magical messages from the beyond.

There?s plenty of people who claim to be psychics or mediums but watch how they wiggle away when you ask for something to prove what they say.

Suggestion by Richard Fleming
hallucinating usually comes from some form of brain mis-function or something else to cause the brain to hallucinate or the other possibility is the use of different drugs. psychic ability is something that i don?t put much stock in. most people that claim this ability are either seriously deceived or living in a constant state of hallucination.

Know better? Leave your own answer in the comments!

You also can BOOKMARK us here and share it your Friends here...

And if you have any question for this song or video plase contact us by contact form here...!

Free Online Psychic Question Website

Support Team

Source: http://freeonlinepsychicquestion.com/why-do-i-feel-like-i-have-psychic-abilities

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Sunday, February 3, 2013

Movie Review: 'Warm Bodies' an Awesome Zombie Valentine ...

No, it's not an ode to necrophilia. It is a charming and whimsical movie that goes deeper than anyone would expect about connectedness, trust and a willingness to change.?

I never thought I'd say "this zombie flick is a great date movie," but now I have. As a matter of warning, it should be rated "Z" for brain-eating zombies. Still, a large cross-section of movie lovers will enjoy it, making it a far better choice?February 14th?than that new Diehard (coming out that day! Wah?),?for everyone from girlfriends hanging out and Twihards, to couples who don't mind a bit of edge in their flicks.?

Playing at AMC Hoffman Center 22.?

To all those who have heard or bought into the press about it being a wannabe Twilight clone, I say yes, the Twihards will appreciate it. But it will be even more appreciated by all of us who grew tired of Twilight's whining and negativity (however much it was dressed in sparkle), and those of us who wanted to scream at that mopey sad-sack Edward to suck it up and get an afterlife.

Warm Bodies plays fast and loose with zombie rules

Here, in this movie, the undead are anything but resigned to their plight. ? Warm Bodies has an optimism, unabashed romanticism and earnestness that is perfect for a holiday about love.?It might be too much for the most cynical filmgoers, even with the dried blood and rotting body bits with which it's smeared. ?

Stay far away if you only like your zombies terrifying and the stuff of nightmares. Stay away as well if you are a stickler for the rules of zombie-ism, as you will find Warm Bodies plays a little too fast and loose with those rules.? As yet another mash-up, this time of zombies and coming-of-age romcoms (a "zomcom," if you will) Cinema Siren does believe it adds something worthwhile to both genres.?

The story is about R, a zombie who lets us into his conflicted, less-dead-than-we-think brain, as he trudges with the rest of the rotting pack. He takes a Cupid's bullet to the heart when he sees gun-toting Julie, out with her med-foraging friends, about to become the next zombie Happy Meal. He rescues her and whisks her away to the nick-nack-filled jet airplane this nostalgic zombie packrat calls home, where they share a few sweetly awkward days and nights getting to know each other.?

Actor Nicholas Hoult, as 'R,' is the star

Love spreads like a scarlet pillow? The rest of the movie is them against the world, which includes Julie's protective dad (the underused John Malkovitch), a post-apocalyptic general with a quick trigger finger for all things undead. ?

Aussie ingenue Teresa Palmer, who forever strains against the label of the "blonde Kristen Stewart," does well enough as Julie, the love interest for an undead 20-something who finds he feels more and more alive when she is near.?

R is the star. Actor Nicholas Hoult (About A Boy, X-Men: First Class) is the one who must carry the film on his slumped and shambling frame. He plays a character who feels isolated, misunderstood and trapped inside a shell that belies his inner sweetness.?

Director enhances novel on the big screen

It's probably hard to make friends and make time when you smell like death, speak in grunts and eat human flesh to survive. He works his way through a wide range of emotions, in scenes that require him to play both broadly and with subtlety in quick succession. ?With natural talent, expanding skill and now adult and undeniable good looks, Hoult will catapult himself into position as an "A" actor with his pick of constantly revolving projects. ?

Rob Coddry's "M," R's "BZF," allows the actor to bring his great character acting and perfect timing to the proceedings, and gets big laughs that mean his memorable role might quickly become a fan favorite. He makes impressive use of scant screen time, further perking up the auds with his every arrival.

Director and screenplay writer Jonathan Levine (who made the surprisingly successful cancer dramedy 50/50) makes the depth of the original novel, written by Isaac Marion, translate very well to the screen, keeping and sometimes even enhancing the metaphoric lessons both great and small, which range from tackling racism and bigotry, to youth alienation, to cocooning and isolation in the computer age.?

There is also a literary reference you might already have heard about or figured out that is far more meaningful if you know well the original from which it takes inspiration.

Soundtracks builds emotional atmosphere

The soundtrack proves to be a mix of clever and poignant. Levine allows the music, some of which is made up of cheesy '80s hits you'll never hear the same way again, to be an integral part of the scene. It builds an emotional atmosphere and adds a component that connects with the audience during the extended times where voiceover narration and slowly shuffling zombies might call a screeching halt to the movie's forward movement. The best soundtracks do that.

To be sure, the end of the movie arrives in a swell of sweet that might as well have us all singing Todd Rundgren's "Love Is The Answer," but that's what romcoms do. The difference is this is a zomcom. Either you can abide this funky freaky little film, with its conceits and exposed beating heart or you can't.

I can, and I absolutely loved it. You might find you do, too. One thing's for sure, your significant other is probably not going to be willing to sit through The Walking Dead on Valentine's Day. With Warm Bodies, you get zombies and love, all tied up in a big bloody-caked bow. Make it a Valentine's Day present to yourself. ?

Source: http://mountvernon.patch.com/articles/movie-review-warm-bodies-an-awesome-zombie-valentine-1bcc4e0d

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Thursday, January 31, 2013

China sentences two Tibetans for "inciting" self-immolations

BEIJING (Reuters) - A court in China has handed down heavy sentences to a Tibetan monk and his nephew for inciting eight people to set themselves on fire in anti-Chinese protests, media said on Thursday, the first time punishment has been meted out over such protests.

Nearly 100 Tibetans have set themselves on fire to protest against Chinese rule since 2009, with most of them dying from their injuries.

Lorang Konchok, 40, was sentenced to death with a two-year reprieve in the Aba prefecture in Sichuan province, while his nephew, Losang Tsering, 31, was sentenced to 10 years in prison, the Xinhua state news agency said.

In practice, a death sentence with a two-year reprieve is commuted to life imprisonment or reduced to a fixed-term later.

"The two incited and coerced eight people to self-immolate, resulting in three deaths," Xinhua said, citing the Intermediate People's Court in Aba prefecture.

Last December, Xinhua reported that Lorang Konchok, who was detained with his nephew in August, confessed to police that he had followed instructions from exiled Tibetan spiritual leader the Dalai Lama and his followers.

Lorang Konchok and his nephew passed on information about each self-immolation, including photographs, to overseas contacts belonging to a Tibetan independence organisation with mobile telephones, Xinhua said.

China has repeatedly denounced the Dalai Lama and exiled Tibetan groups for fomenting the self-immolations.

Beijing considers Nobel peace laureate the Dalai Lama, who fled from China in 1959 after an abortive uprising against Chinese rule, a separatist. The Dalai Lama says he is merely seeking greater autonomy for his Himalayan homeland.

He has called on China to investigate the self-immolations. He has said he is not encouraging them has called them "understandable".

China has defended its iron-fisted rule in Tibet, saying the remote region suffered from dire poverty, brutal exploitation and economic stagnation until 1950, when Communist troops "peacefully liberated" it.

Tibetan areas in China have been largely closed to foreign reporters, making an independent assessment of the situation there impossible.

Chinese police arrested a Tibetan man last week for allegedly encouraging a monk to burn himself to death, as part of a new tactic to discourage suicide protests against Chinese rule.

(Reporting by Sui-Lee Wee; Editing by Robert Birsel)

Source: http://news.yahoo.com/china-sentences-two-tibetans-inciting-self-immolations-054011821.html

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Wednesday, January 30, 2013

Immigration reform: Will 'amnesty' produce more illegal immigration?

Immigration reform is in the air. A bipartisan Senate group unveiled its proposals on Monday, and the president is scheduled to announce his own package on Tuesday. Both contain provisions for legalizing some 11 million undocumented immigrants now in the US.

But, just as there promises to be no easy consensus on a final deal, there is little agreement about how much the overall reforms will actually stem the flow of illegal immigration across America?s borders. Critics of the proposals say a path to citizenship invites more undocumented migrants, while supporters of the move to legalize many who have lived and worked in the US for years say it is not an open invitation to new illegal immigration.

Critics point to the lessons from the last time Congress tackled his issue, the Immigration Reform and Control Act (IRCA), a 1986 law that legalized 3 million undocumented immigrants. Both sides acknowledge the law produced substantial fraud, leading to nearly triple the number of new residents created by the law.

RECOMMENDED: Could you pass a US citizenship test?

"The message will go out,? says Ira Mehlman, Seattle-based national spokesman for the Federation for American Immigration Reform (FAIR), ?telling people to bring their rent receipts and pay stubs real or not.? The situation will be a replay of the 1986 law, only on a larger scale, he says. It?s simple math, says Mr. Mehlman, adding, ?how can you possibly do background checks on 11 million people? It just won?t happen.?

This expectation sells this target population short, says Jorge-Mario Cabrera, spokesman for the Coalition for Humane Immigrants Rights of Los Angeles (CHIRLA). ?Nobody wants to go where they are not wanted and cannot legally find a job to support them or their family,? he says. ?I do not foresee a wave of illegal immigration, because most of these people realize the political situation in the US is very dire when it comes to undocumented immigrants.?

Census data released at the end of 2012 show a slowing of the immigration tide. The number of undocumented immigrants fell to 11.1 million, down from a high of some 12 million in 2007, following more than a decade of increases. A Pew Center analysis of these data finds that ?there is net zero migration taking place from Mexico to the United States,? points out Villanova University immigration specialist Catherine Wilson, via e-mail.

The proposed reforms will not encourage illegal immigration in the future for three reasons, says David Koelsch, director the Immigration Law Clinic at the University of Detroit Mercy School of Law.

  • The proposed pathways to legal status will be long and expensive, he says via e-mail, ?So any reward for future illegal immigration is distant.?
  • The birth rate in Mexico is in rapid decline and domestic industry's wages are rising, ?making the US less attractive,? he says.
  • The US economy is still not recovered, "so there is not a strong draw for illegal immigration,? he adds. A sustained 1.75 to 2.25 percent growth rate does not even keep our native population employed, he says.

The reality ?is that our border is more secure than it has been in years past and as immigration talks heat up, our border agents and patrol will be well aware of the need for greater vigilance,? says immigration lawyer and law professor Michael Wildes, who is managing partner of Wildes & Weinberg in New York City and represented the government in immigration cases in his time as a US Attorney.

The law needs to have enough teeth that it doesn't open the door to greater illegal immigration, he adds. ?Whether that means tougher sanctions or steeper fines is up to Congress to decide. But the penalties need to be more stringent because once a pathway to citizenship is defined, there is even less of an excuse for employers to hire undocumented workers and for folks to come here illegally and remain illegal.?

While the numbers tell a story of declining illegal immigration, still a path to citizenship for those now in the country illegally may be a political problem for those who want to pass comprehensive immigration legislation, says David Mark, editor-in-chief of the website, Politix.

?It just seems like common sense to most people that if you make it easier to become legal, that will attract others as well,? he adds. ?It is naive to think otherwise.?

RECOMMENDED: Could you pass a US citizenship test?

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Source: http://news.yahoo.com/immigration-reform-amnesty-produce-more-illegal-immigration-013500775.html

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Friday, January 25, 2013

Welfare lottery ban: N.C. lawmakers discuss prohibition for welfare recipients, the bankrupt

Rep. Paul 'Skip' Stam (R-Wake) said the measure is among several targeting the N.C. Education?Lottery?that may come up during the legislative session.

By Associated Press / January 25, 2013

North Carolina lawmakers are discussing a draft proposal that would prohibit sales oflottery?tickets to people who receive public assistance or who are in bankruptcy.

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The Insider reports?that Rep. Paul "Skip" Stam, R-Wake, said the measure is among several targeting the N.C. Education?Lottery?that may come up during the legislative session.

"We're giving them?welfare?to help them live, and yet by selling them a ticket, we're taking away their money that is there to provide them the barest of necessities," Stam said.

Stam it would be difficult for store clerks to know which players get help. But Stam suggested that in obvious cases, such as when customers pay for groceries with food stamps, they shouldn't be allowed to buy?lotterytickets at the same time.

Another proposal would remove the word "Education" from the N.C. Education?Lottery?for advertising purposes. Stam said the word "education" shouldn't be used to sell "something that is essentially a scam," especially because?lottery?proceeds account for a small percentage of state education funding.

"It's just inappropriate to take what is a very important function of state government ... and use that as a selling point, when obviously the more educated you are, the less likely you are to play the?lottery," he said.

Stam said he believes many?lottery?ads are deceptive because they don't state the probabilities of winning particular prize amounts. The?lottery?advertises large cash payouts, he said, but the actual prizes are smaller after taxes and other deductions. The fact that the?lottery?doesn't give the actual values of prizes when advertising larger amounts is "just fraudulent," he said.

Alice Garland, executive director of the?lottery, said last week that she believed taking "Education" out of the title would cut into?lottery?sales.

Lottery?spokesman Van Denton said officials haven't fully reviewed all of the legislative proposals to gauge the impacts, but he did say the?lottery?tries to keep up with best practices in the industry, he said.

"We work hard to make sure players have the information they need to play the?lottery?... and to make good choices about how to spend their money," Denton said.

Although the odds of winning each different prize amount aren't listed on each ticket, they are available on thelottery?website and in the?lottery?"play centers" at retail locations. The?lottery?also publishes on its website the number of prizes remaining at all prize levels in scratch-off games.

Source: http://rss.csmonitor.com/~r/feeds/csm/~3/Lxhi8SZRZDE/Welfare-lottery-ban-N.C.-lawmakers-discuss-prohibition-for-welfare-recipients-the-bankrupt

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Diverse Slate of Established, New Authors to Speak at Weeklong ...

Wednesday, January 23rd, 2013
Issue 04, Volume 17.


RIVERSIDE - Established authors, poets and creative writing professors will share insights regarding what it takes to get published during UC Riverside's 36th annual "Writers Week," which begins Feb. 4.

"We have an amazing line-up this year," said Tom Lutz, a UCR creative writing professor and editor-in-chief of the Los Angeles Review of Books. "As Southern California's longest-running literary event, Writers Week provides extraordinary opportunities for LARB. For writers, the combination is great, especially writers who are launching new books."

Opening day will feature a lecture by Los Angeles Times Editor-in-Chief Davan Maharaj, who will assess contemporary journalism and spotlight where he believes the industry is going.

The reservation-only talk is scheduled for 7:30 p.m., Feb. 4, at the UCR University Theatre.

Several of the campus's resident authors, including Tod Goldberg, who teaches Writing for Advertisement
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the Performing Arts at UCR-Palm Desert, will be on hand, as well as others involved in the university's Master of Fine Arts Program.

Authors about to debut new works are slated to speak, including Reyna Grande, Ruben Martinez and David Shields.

Poets Jacqueline Berger, Wanda Coleman, Patricia Hampl and Sheila Sanderson will be giving talks, as will novelists Aimee Phan, Jayne Anne Phillips and Mariah Young.

The event will also feature interactive panel discussions and opportunities to engage Writers Week authors one-on-one, as well as purchase their books on-site.

All activities -- free and open to the public -- will be centered at the CHASS Interdisciplinary Building, except for the closing night keynote address, which Phillips is scheduled to deliver at the UCR Culver Center of the Arts on the downtown Riverside Main Street pedestrian mall.

Source: http://www.myvalleynews.com/story/68939/

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Thursday, January 24, 2013

Pavlov's rats? Rodents trained to link rewards to visual cues

Jan. 23, 2013 ? In experiments on rats outfitted with tiny goggles, scientists say they have learned that the brain's initial vision processing center not only relays visual stimuli, but also can "learn" time intervals and create specifically timed expectations of future rewards. The research, by a team at the Johns Hopkins University School of Medicine and the Massachusetts Institute of Technology, sheds new light on learning and memory-making, the investigators say, and could help explain why people with Alzheimer's disease have trouble remembering recent events.

Results of the study, in the journal Neuron, suggest that connections within nerve cell networks in the vision-processing center can be strengthened by the neurochemical acetylcholine (ACh), which the brain is thought to secrete after a reward is received. Only nerve cell networks recently stimulated by a flash of light delivered through the goggles are affected by ACh, which in turn allows those nerve networks to associate the visual cue with the reward. Because brain structures are highly conserved in mammals, the findings likely have parallels in humans, they say.

"We've discovered that nerve cells in this part of the brain, the primary visual cortex, seem to be able to develop molecular memories, helping us understand how animals learn to predict rewarding outcomes," says Marshall Hussain Shuler, Ph.D., assistant professor of neuroscience at the Institute for Basic Biomedical Sciences at the Johns Hopkins University School of Medicine.

To maximize survival, an animal's brain has to remember what cues precede a positive or negative event, allowing the animal to alter its behavior to increase rewards and decrease mishaps. In the Hopkins-MIT study, the researchers sought clarity about how the brain links visual information to more complex information about time and reward.

The presiding theory, Hussain Shuler says, assumed that this connection was made in areas devoted to "high-level" processing, like the frontal cortex, which is known to be important for learning and memory. The primary visual cortex seemed to simply receive information from the eyes and "re-piece" the visual world together before presenting it to decision-making parts of the brain.

To monitor the vision-reward connection process, the team fitted rats with special goggles that let researchers flash a light before either their left or right eye. Thirsty rats with goggles were given access to a water spout inside a testing chamber. When they approached the water spout, a brief visual cue was presented to one eye.

If light was sent to the left eye, the water spout would have to be licked a few times before water came to the rat; if light was sent to the right eye, the rat would have to lick many more times before water came. After a few daily sessions of such "conditioning" (not unlike Pavlov's famous dog-bell-reward experiments), the rats learned how long they would have to lick before getting a water reward. If they didn't get the reward in the expected amount of time, they would give up and leave the spout.

Monitoring the pattern of electrical signals given off by individual nerve cells in the rat brains, the researchers found that the signals' "spikes" weren't just reflecting the visual cue alone. Rather, the signals seemed to relay the time of expected reward delivery through altered spiking patterns. They also saw that many nerve cells seemed to report one or the other visual cue-reward interval, but not both. In cells stimulated by a flash to the left eye, the electrical signal returned to its baseline after a short delay, in sync with the timing of the water reward; a cue to the right eye correlated with a longer delay, also in sync with the reward. According to the researchers, the amount of time that passed before nerve cells returned to their resting state was the brain's way of setting up a "timed expectation."

Knowing that the basal forebrain is implicated in learning, the researchers wanted to know if their observations could be explained by nerves from the basal forebrain delivering ACh to the vision-processing center. To remove those nerve cells from the equation, they paired a neurotoxin with a "homing device" that targets only ACh-releasing neurons coming from the basal forebrain. They then repeated their experiments in trained rats that received the neurotoxin and in those that didn't, and found that the nerve cell signals continued to relay the old time intervals, suggesting that ACh and the basal forebrain weren't needed to express previously learned time information.

The researchers next used those same rats to ask if ACh is necessary for nerve cells to learn new time delays. To do that, they switched the visual cues so that a flash in the left eye meant a long delay and one in the right eye meant a short one. Vision-processing nerve cells in the rats in which ACh delivery was left intact adapted their signals to the new associations; but those in the rats that no longer received ACh continued to relay the old associations, suggesting that ACh is necessary to make new associations but not to express old ones.

Hussain Shuler explains, "When a reward is received, ACh is sent throughout the brain and reinforces only those nerve cell connections that were recently active. The process of conditioning continues to strengthen these nerve connections, giving rise to a timed expectation of reward in the brain."

According to Hussain Shuler, studies have shown that Alzheimer's patients have low levels of ACh and have trouble forming new memories. Though medication may elevate ACh, alleviation of symptoms is limited. "Our research explains that limitation," he says. "Therapeutically, we predict that the problem isn't just low levels of ACh -- the timing of ACh delivery is key."

Other authors of the report include Emma Roach of the Johns Hopkins University School of Medicine and Alexander Chubykin and Mark Bear of the Massachusetts Institute of Technology.

This work was supported by grants from the National Institute of Mental Health (R01MH084911), the National Institute on Drug Abuse (F31DA026687), the National Eye Institute (R01EYO12309), the National Institute of Child Health and Human Development (R01HD046943) and The Johns Hopkins University.

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